|
|
BENEGENE
Immortality is an age old Holy Grail. A phenomenon of the
ego. A topic best left to science fiction and Hollywood. The
search for it is often beset with tragedy, as was the case of
Juan Ponce De Leon and his quest for the legendary fountain of
youth.
However, life extension is a realistic goal and a proven
physiologic phenomenon in diverse organisms through various
interventions, such as exposure to certain stresses (ionizing
radiations, heat or osmotic shock) or caloric restriction.
There are several ways of extending life span but the key is to
match the gain in years with a corresponding increase in vigour and
vitality. In other words, adding years to life has to be concurrent
with adding life to years. Ideally increasing both maximal life span
and health span. The latter can be assessed by monitoring various
disease-risk markers such as lowered blood glucose levels, Hb1Ac,
isoprostane F2, reactive oxygen and nitrogen species, lipid markers,
age-amadori adducts, and different inflammatory markers such as
C-reactive proteins.
The process of aging has been ascribed to various mechanisms
including:
(1) increased metabolism and thus increased production of
reactive oxygen species (free radicalse),
(2) reduction of apoptosis (or programmed
cell death),
(3) increased glucose/insulin and insulin-like growth
factor 1 (IGF-1) signalling molecules,
(4) disruption of the daf-2
pathway,
(5) effect of longevity genes (including FOXO, Sir-2, and
INDY (I am not dead yet)),
(6) NAD+/NADH ratio, and others.
These all sound very complicated
but actually are simply part of the biochemistry of aging...and that we know of them...we can do something about it!
Caloric restriction optimal nutrition (CRON) extends life and health
span in a wide variety of organisms and has been shown to delay the
onset or reduce the incidence of many age-related diseases,
including cancers, diabetes, cardiovascular diseases and
neurological diseases (including Parkinson’s and Alzheimer’s).
Furthermore, a significant improvement in various disease risk
parameters has been conclusively shown in humans. Those of us in our fifties and older will remember all the hoopla with the Hunza peoples in the Himalayans back in the 60's and 70's. They were known for their long and healthy
lives...eating a very low calorie diet. Science knew they were healthier than most North Americans..but their sparse diet was next to impossible for our population to adhere to. Now, with Benegene, that positive effect can be experienced with a more normal, healthy calorie load.
Thanks to the pioneering work of professors Leonard P. Guarente (of
the Massachusetts Institute of Technology) and David A. Sinclair (of
Harvard University), research has revealed that certain longevity
genes are activated during caloric restriction. Moreover, their work
showed that this effect was evident at any age; in other words, life
extension could be achieved in older age groups as well. Gurante and
other researchers believe that this effect may be related to the
critical ratio of the ubiquitous co-enzymes NAD+ (the oxidized form
of NAD, or nicotinamide adenine dinucleotide) and its reduced form
NADH. NAD is a niacin-derived coenzyme that is present in all living
cells and is critical to the production of ATP – the body’s primary
source of all immediate energy. Higher NAD+ levels are thought to
have a stimulatory effect on the beneficial genes whilst a high NADH
concentration is thought to inhibit such genes. Hence a high
NAD+/NADH ratio may prolong life and health span.
BenaGene™ is a novel caloric restriction mimetic (CR mimetic). It
mimics the changes in the expression of over 350 genes in a similar
fashion to caloric restriction and thus may be considered a true
nutrigenomic compound. The resulting (and astonishing) increases in
average and maximal life span, reduction in weight, and reduction in
glucose levels have been observed in various species.
Human clinical trials have confirmed both reduction in glucose
levels and an improved uptake of glucose without negative side
effects (and hence an effective hypoglycaemic agent). BenaGene™ work
on a “biological diode” thereby increasing the conversion of NADH to
NAD+ as well as on resulting changes in the electrical state (Gibbs
free energy) and critical signalling molecules.
BenaGene™ is the world’s first novel and natural Krebs cycle
intermediate compound that is specifically formulated to be highly
stable and bio-available so that a one-a-day dosage is all that is
required, offering the potential of life and health extension.
BENEGENE |
| Quantity in Basket:none
Code: 9000
Price:$55.00
Shipping Weight: 0.00 pounds
|
|
| | 30 Capsules |
BenaGene™ contains a key intermediate in the
Kreb's Cycle. Studies demonstrate that benaGene mimics a
caloric restriction diet, which has been shown to increase the
expression of beneficial genes associated with increased life
span, health span, weight management and blood glucose
reduction.
30 Vegi-Caps AOR04138
100% Vegetarian
______________________________________________
SUPPLEMENT FACTS:
Serving Size: 1 Capsule
____________________________________________________
benaGene™ (3-carboxy-3-oxopropanoic acid) .......... 100 mg
Vitamin C ..........................................
100 mg
____________________________________________________
*Dietary Reference Intake not established.
Non-medicinal ingredients: Microcrystalline cellulose. Capsule;
hypromellose, sorbitol, silicon dioxide, water, lecithin.
AOR guarantees that no ingredients not listed on the label have been
added to the product. Contains no wheat, gluten, corn, nuts, soy,
eggs, dairy, fish or shellfish.
Suggested Use
Take one capsule daily with food or as directed by a qualified
health practitioner. Do not use during pregnancy and lactation.
Main applications
As reported by literature:
• Anti-Aging.
• Glucose metabolism.
|
|
|
