|
|
NATTOKINASE: A Potent Fibrinolytic Enzyme Extract of Traditional Japanese Food; Landmark
Development
for Cardiovascular Health
What Is Nattokinase?
Nattokinase is a potent fibrinolytic enzyme extracted and
highly purified from a traditional Japanese food called
natto. Natto is a fermented cheese-like food that has been
used in Japan for over 1000 years for its popular taste and
as a folk remedy for heart and vascular diseases. Natto is
produced by a fermentation process by adding Bacillus
subtilis var. natto. a benefical bacteria, to boiled soybeans.
The resulting nattokinase enzyme, is produced when
Bacillus siibtilis var. natto acts on the soybeans. While
other soy foods contain enzymes, it is only the natto
preparation that contains the specific nattokinase enzyme.
Potent Thrombolytic Activity
The human body produces several types of enzymes
for making thrombus, but only one main enzyme for
breaking it down and dissolving it - plasmin. The
properties of nattokinase closely resemble plasmin.
According to Dr. Martin Milner, N.D. from the
Center for Natural Medicine in Portland, Oregon,
what makes nattokinase a particularly potent
treatment, is that it enhances the body's natural ability
to fight blood clots in several different ways; Because
it so closely resembles plasmin, it dissolves fibrin
directly. In addition, it also enhances the body’s
production of both plasmin and other clot-dissolving
agents, including urokinase (endogenous), “in some
ways, Dr. Milner says nattokinase is actually
superior to conventional clot-dissolving drugs. T-
PAs (tissue plasminogen actuators) and urokinase (the pharmaceutical agents) are only effective when
taken intravenously (IV) and often fail simply
because a stroke or heart attack victim^ arteries
have hardened beyond the point where they can be treated by any other clot-dissolving agents
Nattokinase however can help prevent that
hardening with an oral dose of as little as 100 mg a day.1,7
The Prolonged Action of Nattokinase
Nattokinase produces a prolonged action (unlike antithrombin drugs that wear off shortly after IV
treatment is discontinued) in two ways: it prevents
coagulation of blood and it dissolves existing
thrombus. Both the efficacy and the prolonged action
of NK can be determined by measuring levels of
euglobulin fibrmolytic activity (EFA) and fibrin
degradation products (FDP), which both become
elevated as fibrin is being dissolved. By measuring
EFA & FDP levels, activity of NK has been
determined to last from 8 to 12 hours. An additional
parameter for conflrming the action of NK following
oral administration is a rise in blood levels of TPA
antigen (tissue plasminogen activator), which
indicates a release of TPA from the endothelial cells
and/or the liver5'7
The Mechanism Behind Thrombus
Blood clots (or thrombi) form when strands of protein
called fibrin accumulate m a blood vessel, In the heart,
blood clots cause blockage of blood flow to muscle tissue.
If blood flow is blocked, the oxygen supply to that tissue is
cut off and it eventually dies. This can result in angina and
heart attacks. Clots m chambers of the heart can mobilize
to the brain, In the brain, blood clots also block blood and
oxygen from reaching necessary areas, which can result in
senility and/or stroke. 1
Thrombolytic enzymes are normally generated in the
endothelial cells of the blood vessels. As the body ages.
production of these enzymes begins to decline, making
blood more prone to coagulation. This mechanism can lead
to cardiac or cerebral infarction, as well as other
conditions. Since endothelial cells exist throughout the
body, such as in the arteries, veins and lymphatic system.
poor production of thrombolytic enzymes can lead to the
development of thrombotic conditions virtually anywhere
in the body.7
Nattokinase |
| Quantity in Basket:none
Code: 6501
Price:$50.00
Shipping Weight: 0.00 pounds
|
|
| | 90 Vegi-Caps |
Glossary of Terms:
Cardiac Infarction: Heart attack.
Cerebral Infarction: Stroke
Fibrin: A whitish, filamentous protein formed by the action thrombin on fibrinogen and makes up part of coagulum or blood clots.
Fibrinolytic: Pertaining to or causing the breaking up of blood clots.
Infarction; Cardiac or cerebral time death due to failure of blood supply to the area usually caused by a blood clot.
Plasmin; An endogenously produced fibrinolytic enzyme,
PIasminogen; A precursor to plasmin. A protein found in many tissues and body fluids.
Thrombus: A blood clot that obstructs a blood vessel or a cavity of the heart.
Thrombolytic: Pertaining to or causing the breaking up of a thyombus.
TPA: Tissue plasminogen activate
t-PAs; The most commonly used thrombolytic drugs including activase, urikonase, and streptokinase.
Urokinase: An endogenously produced thrombolytic enzyme & also a commonly used thrombolytic drug giver intravanously to cardiac and cerebral infarction patient.
References:
1. Prevent Heart Attack and Stroke with Potent Enzyme that Dissolves Deadly Blood Clots in Hours. Health Sciences Institute March 2002.
2. MaruyamaM, Sumi H. Effect of Natto Diet on Blood Pressure JTTAS, 1995.
3. Sumi H. Hamada H, Nakanishi K, Hiratani H, Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase Acta Haematol 1990:84(3:139-43.
4. Sumi H, Hamada H, Mihara H. A novel strong flbrinolytic enzyme (nattokinase) in the vegetable cheese "natto " International 5 Journal of Fibronolysis and Thrombolysis. Abstracts of the ninth international congress on fibrinolysis, Amsterdam, 1988. Vol 2, Sup,1:67.
5. Sumi H, Hamada H, Tsushima H, Mihara H, Muraki H. A novel fibrinotytic emyme (nattaknase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet. Experientia 1987, Oct 1.5;43(10):1110-1
6. Sumi H. Healthy Microbe "Bacillus natto”. Japan Bio Science Laboratory Co. Ltd.
7. Sumi H. Interview With Doctor of Medicine Hirayuki Sumi, Japan Bi0 Sience Laboratory Co. Ltd.
8. Sumi H. Structure and Fibronolytic Properties of Nattokinase.
|
|
|
